Lithium, despite its simple structure, has numerous biological effects. It also has a remarkable therapeutic effect in the prophylactic treatment of manic depression, and is finding a role in controlling aggressive and self‐mutilating behavior. The special feature of lithium is that it only acts on overactive systems to bring them back to normal, without affecting the stable system. The mechanisms of action of this simple cation are still largely unknown although the inositol depletion theory is the most widely accepted model. (...) A recent paper(1) described a different molecular mechanism for its effect on development, which may also explain its action in manic depression. (shrink)

Papers presented at the conference held in 2003-2004 at Ahmedabad, India, organized by Department of Philosophy, Gujarat University.

Classical work of Hindu philosophy; with 51 Sanskrit commentaries.

Classical verse work, with commentary by Ānandabodhendrasarasvatī, expounding early Advaita philosophy.

Analytical study of the concept of creation and perception in Vedāntasiddhāntamuktāvalī, treatise on Hindu Advaita (non-dualistic) Vedanta philosophy by Prakāśānanda, 16th cent.

On the life and works of Muni Vidyāraṅya, Advaita thinker and empire builder.

Study of Tattvacintāmaṇididhiti of Raghunātha Śiromaṇi, commentary on Pakṣatā, portion of Tattvacintāmaṇi of Gaṅgeśa, dealing with the essential nature of proposition (pakṣatā), of Navya Nyāya school in Hindu philosophy.

Festschrift in honor of Visvamūrti Śāstrī, born 1946, Sanskritist; comprises contributed articles on his life and works, Vedic and Sanskrit literature.

On philosophy; transcript of the 1978-1979 Śāradā-vyākhyāna-mālā lecture, under the auspices of Sri Lal Bahadur Shastri Rashtriya Vidyapeeth, New Delhi.

Motilal Shastri developed an ethical theory which closely resembles rule utilitarianism at roughly the same time as and yet in complete independence of English-speaking philosophers. The philosophic significance of his view lies in the manner in which he develops and justifies his position. Shastri contends that efficiency in action requires indifference or inattention to ends. He appears to use the same device for justifying rule-governed duties that Mill uses to justify a move from egoism to altruism: that actions first viewed (...) as means may later become ends in themselves. However, in Shastri’s theory, ends appear to be retained as unconscious motives. (shrink)

Motilal Shastri developed an ethical theory which closely resembles rule utilitarianism at roughly the same time as and yet in complete independence of English-speaking philosophers. The philosophic significance of his view lies in the manner in which he develops and justifies his position. Shastri contends that efficiency in action requires indifference or inattention to ends. He appears to use the same device for justifying rule-governed duties that Mill uses to justify a move from egoism to altruism: that actions first viewed (...) as means may later become ends in themselves. However, in Shastri’s theory, ends appear to be retained as unconscious motives. (shrink)

Utpaladeva (c. 900–950 C.E.) was the chief originator of the Pratyabhijñā philosophical theology of monistic Kashmiri Śaivism, which was further developed by Abhinavagupta (c. 950–1020 C.E.) and other successors. The Ajaḍapramātṛsiddhi, “Proof of a Sentient Knower,” is one component of Utpaladeva’s trio of specialized studies called the Siddhitrayī, “Three Proofs.” This article provides an introduction to and translation of the Ajaḍapramātṛsiddhi along with the Vṛtti commentary on it by the nineteenth–twentieth century paṇḍit, Harabhatta Shastri. Utpaladeva in this work presents “transcendental” (...) arguments that a universal knower (pramātṛ), the God Śiva, necessarily exists and that this knower is sentient (ajaḍa). He defends the Pratyabhijñā understanding of sentience against alternative views of both Hindu and Buddhist schools. As elsewhere in his corpus, Utpaladeva also endeavors through his arguments to lead students to the recognition (pratyabhijñā) of identity with Śiva, properly understood as the sentient knower. (shrink)

In the early twentieth century, the vernacular science periodical emerged as a key medium for building science-literate publics in colonial South Asia. This article argues that the Hindi science monthly Vigyan became a discursive laboratory for experiments with language, literary genres, narrative plots, and settings to create culturally grounded science lessons for Hindi readers in the mid-1910s. I focus on the writings of Prem Vallabh Joshi, a pandit, science graduate, and small town teacher, who experimented with distinct literary genres to (...) create a sensibility for science – an experimental temper – amongst Vigyan’s readers. Through his strategic use of scientific experiments in the “history of” a particular branch of knowledge, detective mysteries, and the genre of the fictionalized dialogue, Joshi inducted colonial readers into experimental culture and global scientific modernity. As a reflexive participant in the ongoing confrontation between “Western” science and Hindu śāstra in colonial society, Joshi staged a fictional encounter between the experimental demonstration of the iconic air-pump and the textual authority of śāstra. This article examines the encounter between sastric commitments and scientific sensibilities and their conjoined mobilization in Vigyan in the era of linguistic nationalism. In this colonial vernacular publishing culture, the serial possibilities of the periodical and the history of science itself became critical resources in the ontological confrontations between experimental science and traditional authority. (shrink)

Contributed seminar papers presented at Seminar on the subject of Siddhantavada, organized by Department of Nyayavaisheshika, Shri Lalbahadur Shastri Kendriya Sanskrit Vidyapeeth, New Delhi in 2016.

Shastri & Ajjanagadde argue convincingly that both structured connectionist networks and parallel dynamic inferencing are necessary for reflexive reasoning - a kind of inferencing and reasoning that occurs rapidly, spontaneously, and without conscious effort, and which seems necessary for everyday tasks such as natural language understanding. As S&A describe, reflexive reasoning requires a solution to thedynamic binding problem, that is, how to encode systematic and abstract knowledge and instantiate it in specific situations to draw appropriate inferences. Although symbolic artificial intelligence (...) systems trivially solve the dynamic binding problem using computers' registers and pointers, it has remained a difficult problem for connectionist systems. S&A's temporal synchrony solution to the dynamic binding problem using synchronous firing of argument units and the entities that are bound to them illustrates one way in which connectionist networks can do thisusing a constrained but important class of long-term knowledge rules. Their structured connectionist solution allows dynamic inferencing to proceed in parallel and therefore has a number of advantages for reflexive reasoning over most other connectionist and symbolic systems. (shrink)

Contributed seminar papers on Kashmir Śaivism and Buddhist philosophy, held from March 24, 2012 to March 26, 2012, organized by Shri Lal Bahadur Shastri Rashtriya Sanskrit Vidyapith, New Delhi.

Description: T.R.V. Murti was an original and leading thinker among the Indian philosophers of the twentieth century. He had a brilliant philosophical mind, a love of analysis and argument, and a respect for texts, especially the ones with which he disagreed, as seen in his most important book, The Central Philosophy of Buddhism. With both traditional Shastri training and a Western style Ph.D., Murti was able to bring both strengths to his writing and teaching. Murti knew everything by heart, all (...) the Sutra texts, the Upanisads and other philosophical classics, Panini s grammar, and Patanjali s Great Commentary and other core texts. Upon that foundation, he evaluated doctrines and ideas. Though a philosopher of the classical type, he was also alive to the latest philosophical currents of his day and effectively related the wisdom of traditional teaching to the contemporary questions. It was this last quality that made him a most sought after teacher by students from around the world. Murti spoke with such eloquence and authority that few would dare to interrupt him. He represented the best of Indian philosophical tradition to the world through his teaching at places such as Oxford, Copenhagen, Harvard, Hawaii, and McMaster University in Canada. This book offers an overview and assessment of Murti s scholarship on Buddhism in its Brahmanical context, Advaita Vedanta and Buddhism, Philosophy of Language and Philosophy of spirit. The book begins with a biography of Murti and a discussion of the philosophical influences upon him. Also included is a complete list of Murti s writings. (shrink)

This paper is a commentary on the target article by Lokendra Shastri & Venkat Ajjanagadde [S&A]: “From simple associations to systematic reasoning: A connectionist representation of rules, variables and dynamic bindings using temporal synchrony” in same issue of the journal, pp.417–451. -/- It puts S&A's temporal-synchrony binding method in a broader context, comments on notions of pointing and other ways of associating information - in both computers and connectionist systems - and mentions types of reasoning that are a challenge to (...) S&A's system (amongst many other connectionist systems, recognizing that S&A's is much more capable as regards reasoning than most other contemporary systems). (shrink)

Richard Janko's acclaimed translation of Aristotle's _Poetics_ is accompanied by the most comprehensive commentary available in English that does not presume knowledge of the original Greek. Two other unique features are Janko's translations with notes of both the _Tractatus Coislinianus_, which is argued to be a summary of the lost second book of the Poetics, and fragments of Aristotle’s dialogue On Poets, including recently discovered texts about catharsis, which appear in English for the first time.

Ṣadr, Muḥammad Bāqir; Islamic philosophy; 20th century.

Classical Sanskrit commentary on Brahmasūtra; includes original Sanskrit text with English translation.

A brief presentation of the major conclusions contained in the recently published monograph entitled "The Ascent to Law: Searches and Solutions," written over a period of many years. Chapter headings are: The law - an objective reality. The dogma of the law. The drama of scholarship. Searching. "The entire" substance of the law. Juridical constructs. The logic of laws. The secret of the law. Law - the highest purpose. Law in the life and fate of mankind.

The article discusses two bioart projects that bring the symbolically core human substances of blood, sweat and tears into technologically mediated relationships with plants and fungi to explore human kinship with other species: Tarah Rhoda’s BS&T (short for ‘blood, sweat and tears’) and OurGlass, and Saša Spačal’s MycoMythologies: Patterning. The article analyses the art projects through the lens of the molecular gaze and different perspectives on kinning, bringing anthropological conceptualizations of kinship together with Haraway’s pathways to connect with other species. (...) How can bioart use technologies to explore interspecies kinship through a molecular gaze? And may such artworks contribute to the toning down of human exceptionality in the face of a precarious future? We find that artworks providing a molecular gaze on interspecies biological processes may risk a decontextualized approach to complex relational processes but may also create new visions of filiation even with biological organisms imagined to be genetically distant from humans, thus spurring awareness of the fragile interrelationships among species. (shrink)

Introduction:To meet and take care of people with dementia implicate professional and moral challenges for caregivers. Using force happens daily. However, staff also encounter challenges with the management in the units. Managing the caretaking function is also significant in how caretakers experience working in dementia care.Purpose:The purpose of this study is to explore the caregiver’s experiences with ethical challenges in dementia care settings and the significance of professional leadership in this context.Method:The design is qualitative, and data appear through narrative interviews. (...) A total of 23 caretakers participated in the study. The transcribed interviews were subjected to a phenomenological-hermeneutical interpretation.Ethical considerations:The respondents signed an informed consent for participation prior to the interviews. They were assured anonymity and confidentiality in the publication of the data. Ricoeur’s method for interpretation ensures anonymity as the researcher relates to the data as one collective text. The study is part of a larger research project in ethics, in its entirety approved in line with the Helsinki Convention.Results:The findings show that the caretakers experienced inadequacy. Some of them described a negative work atmosphere where they experienced that their leaders did not take them seriously. Because of this, informal negative sub-groups functioned as an exclusive debriefing arena. Some of the informants described the opposite experience where the leaders actively supported them.Discussion:The analyses of the findings are discussed in light of the concepts of trust and mistrust in leadership.Conclusion:There is a correlation between the leadership and the caregivers’ experience of being in difficult situations. (shrink)

The Principles of Biomedical Ethics by Beauchamp and Childress is a classic in the field of medical ethics. The first edition was published in 1979 and “unleashed” the four principles of respect for autonomy, non-maleficence, beneficence, and justice on the newly emerging field. These principles were argued to be mid-level principles mediating between high-level moral theory and low-level common morality, and they immediately became very popular in writings about medical ethics. Over the years Beauchamp and Childress have developed this approach (...) and vigorously defended it against the various criticisms that have been raised. The 5th edition of this book is, as all the …. (shrink)

Theologians are split into two groups: those who embrace prosperity theology and those who oppose it; both sides on scriptural grounds. Those criticising it embrace cessationism in its diversity, while its supporters are mainly found among Pentecostals and Charismatics, who are continuationists. Continuationists believe and teach that all gifts of the Spirit are still available to the church today, therefore should be practised by the church just as they were operative during the apostolic era. Therefore, it is clear that prosperity (...) preachers are continuationists. They believe and practice healing and miracle gifts today. A review of the literature, biblical texts, historical teachings, and Pentecostal and Neo-Pentecostal (also referred to as charismatic and neo-charismatic) form the basis of this article. It addresses the positive features of prosperity teachers’ beliefs and methods as well as how they exploit the dreams, fears, and aspirations of people living in poverty. The theology of sharing, as articulated by Nicholas B.H. Bhengu, is proposed as a solution to creating parity between the rich and the poor.Contribution: This article seeks to balance opposing theological approaches with the prosperity gospel. It does this by introducing a theology of sharing as taught by Nicholas Bhengu based on the philosophy of Ubuntu, a way of life among African people. The challenge for theologians on both sides of the argument is finding a way to accommodate the other side’s contributions. (shrink)

Human agents draw a variety of inferences effortlessly, spontaneously, and with remarkable efficiency – as though these inferences were a reflexive response of their cognitive apparatus. Furthermore, these inferences are drawn with reference to a large body of background knowledge. This remarkable human ability seems paradoxical given the complexity of reasoning reported by researchers in artificial intelligence. It also poses a challenge for cognitive science and computational neuroscience: How can a system of simple and slow neuronlike elements represent a large (...) body of systemic knowledge and perform a range of inferences with such speed? We describe a computational model that takes a step toward addressing the cognitive science challenge and resolving the artificial intelligence paradox. We show how a connectionist network can encode millions of facts and rules involving n-ary predicates and variables and perform a class of inferences in a few hundred milliseconds. Efficient reasoning requires the rapid representation and propagation of dynamic bindings. Our model (which we refer to as SHRUTI) achieves this by representing (1) dynamic bindings as the synchronous firing of appropriate nodes, (2) rules as interconnection patterns that direct the propagation of rhythmic activity, and (3) long-term facts as temporal pattern-matching subnetworks. The model is consistent with recent neurophysiological evidence that synchronous activity occurs in the brain and may play a representational role in neural information processing. The model also makes specific psychologically significant predictions about the nature of reflexive reasoning. It identifies constraints on the form of rules that may participate in such reasoning and relates the capacity of the working memory underlying reflexive reasoning to biological parameters such as the lowest frequency at which nodes can sustain synchronous oscillations and the coarseness of synchronization. (shrink)

Analyzes the origin, structure and resolution of Kant's antinomies of reason from a systematic rather than a historical perspective, exploring the relationship between the theoretical antinomies and the practical antinomy in order to indicate their similarities and differences and to suggest the dependence of the latter on the former.